After nine weeks on the Darzalex, my M-protein level continues to plummet:

This isn’t quite a new record low (that would be 0.3 on May 6, 2016), but it’s pretty close. I expect that next month’s reading will be the lowest I’ve registered since I was first diagnosed with multiple myeloma. So that’s good news.

Now, you may recall that there’s some not-so-good news that goes along with this: the Darzalex kills off all the antibodies in its path, not just the cancerous ones. In my case, it’s the IgG antibodies that are cancerous, but the Darzalex also blew through my IgA antibodies, reducing them from 200 to 19. That’s a big reduction. This week they’re down to 12.

No one has called me with panic in their voice and instructions to curl up in an isolation booth, so I suppose it can’t be all that bad. On the other hand, I wonder if low antibody counts are related to tiredness? Damn, but I sleep a lot these days. I’m averaging 10-12 hours a day lately: about 8 hours at night and then 3 or 4 hours during the day. That’s a lot of sleep.

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WE'LL BE BLUNT

It is astonishingly hard keeping a newsroom afloat these days, and we need to raise $253,000 in online donations quickly, by October 7.

The short of it: Last year, we had to cut $1 million from our budget so we could have any chance of breaking even by the time our fiscal year ended in June. And despite a huge rally from so many of you leading up to the deadline, we still came up a bit short on the whole. We can’t let that happen again. We have no wiggle room to begin with, and now we have a hole to dig out of.

Readers also told us to just give it to you straight when we need to ask for your support, and seeing how matter-of-factly explaining our inner workings, our challenges and finances, can bring more of you in has been a real silver lining. So our online membership lead, Brian, lays it all out for you in his personal, insider account (that literally puts his skin in the game!) of how urgent things are right now.

The upshot: Being able to rally $253,000 in donations over these next few weeks is vitally important simply because it is the number that keeps us right on track, helping make sure we don't end up with a bigger gap than can be filled again, helping us avoid any significant (and knowable) cash-flow crunches for now. We used to be more nonchalant about coming up short this time of year, thinking we can make it by the time June rolls around. Not anymore.

Because the in-depth journalism on underreported beats and unique perspectives on the daily news you turn to Mother Jones for is only possible because readers fund us. Corporations and powerful people with deep pockets will never sustain the type of journalism we exist to do. The only investors who won’t let independent, investigative journalism down are the people who actually care about its future—you.

And we need readers to show up for us big time—again.

Getting just 10 percent of the people who care enough about our work to be reading this blurb to part with a few bucks would be utterly transformative for us, and that's very much what we need to keep charging hard in this financially uncertain, high-stakes year.

If you can right now, please support the journalism you get from Mother Jones with a donation at whatever amount works for you. And please do it now, before you move on to whatever you're about to do next and think maybe you'll get to it later, because every gift matters and we really need to see a strong response if we're going to raise the $253,000 we need in less than three weeks.

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