African-Americans Genetically Prone to HIV, AIDS

Let our journalists help you make sense of the noise: Subscribe to the Mother Jones Daily newsletter and get a recap of news that matters.


New research shows that Africans and African-Americans bear a gene variant that helps protect them from malaria, but also makes them more vulnerable to HIV infection. The variant increases susceptability to HIV by 40 percent, says the San Francisco Chronicle.

The genetic trait is found in 90 percent of Africans and 60 percent of African-Americans. Thus far, it has protected against malaria by disabling a protein that some strains of malaria use to enter red blood cells. However, that same protein that’s disabled in Africans to prevent malaria can actually protect against HIV by soaking up virus cells before they can invade white blood cells. With this sponge-like protein disabled, Africans lose a key pre-infection barrier.

This finding helps explain, in part, the high HIV infection rates among Sub-Saharan Africans and Americans of African descent. On the flipside, there is a genetic variant among people of Northern European heritage that actually makes them immune to HIV infection. Scientists think the mutation was passed down by ancestors who survived the Black Plague. In one test, a man’s blood was exposed to 3,000 times the amount of HIV needed to infect a cell, but infection still didn’t occur. The HIV virus simply had no gateway of entry.

Both the European and African genetic traits are currently being studied to see if they can shed light on a cure to HIV.

SIX TRUTHS

Reclaiming power from those who abuse it often starts with telling the truth. And in "This Is How Authoritarians Get Defeated," MoJo's Monika Bauerlein unpacks six truths to remember during the homestretch of an election where democracy, truth, and decency are on the line.

Truth #1: The chaos is the point.

Truth #2: Team Reality is bigger than it seems.

Truth #3: Facebook owns this.

Truth #4: When we go to work, we're in the fight.

Truth #5: It's about minority rule.

Truth #6: The only thing that can save us is…us.

Please take a moment to see how all these truths add up, because what happens in the weeks and months ahead will reverberate for at least a generation and we better be prepared.

And if you think journalism like Mother Jones'—that calls it like it is, that will never acquiesce to power, that looks where others don't—can help guide us through this historic, high-stakes moment, and you're able to right now, please help us reach our $350,000 goal by October 31 with a donation today. It's all hands on deck for democracy.

payment methods

SIX TRUTHS

Reclaiming power from those who abuse it often starts with telling the truth. And in "This Is How Authoritarians Get Defeated," MoJo's Monika Bauerlein unpacks six truths to remember during the homestretch of an election where democracy, truth, and decency are on the line.

Truth #1: The chaos is the point.

Truth #2: Team Reality is bigger than it seems.

Truth #3: Facebook owns this.

Truth #4: When we go to work, we're in the fight.

Truth #5: It's about minority rule.

Truth #6: The only thing that can save us is…us.

Please take a moment to see how all these truths add up, because what happens in the weeks and months ahead will reverberate for at least a generation and we better be prepared.

And if you think journalism like Mother Jones'—that calls it like it is, that will never acquiesce to power, that looks where others don't—can help guide us through this historic, high-stakes moment, and you're able to right now, please help us reach our $350,000 goal by October 31 with a donation today. It's all hands on deck for democracy.

payment methods

We Recommend

Latest

Sign up for our free newsletter

Subscribe to the Mother Jones Daily to have our top stories delivered directly to your inbox.

Get our award-winning magazine

Save big on a full year of investigations, ideas, and insights.

Subscribe

Support our journalism

Help Mother Jones' reporters dig deep with a tax-deductible donation.

Donate